A incidência de complicações cardiovasculares associadas à COVID-19 em portadores de Diabete Mellitus: uma revisão sistemática
DOI:
https://doi.org/10.60104/revhugv10018Palavras-chave:
Covid-19. DM. Diabete Mellitus. Doenças Cardiovasculares. SARS-COV-2.Resumo
INTRODUÇÃO: O Diabetes mellitus (DM) é um grupo de distúrbios metabólicos caracterizados por hiperglicemia sérica. Diabéticos desenvolvem mais facilmente complicações graves, principalmente cardiovasculares, infecciosas e imunológicas. A COVID-19 é uma doença causada pelo SARS-CoV-2 que, além de pneumonia, pode ocasionar danos a outros órgãos, gerando sequelas gastrointestinais, neurológicas e cardiovasculares. Portadores de DM têm tendência a maior condição inflamatória do que não portadores e, portanto, são propensos ao agravamento de síndromes respiratórias decorrentes da COVID-19 e a complicações cardíacas. OBJETIVOS: Revisar literatura existente acerca das relações entre COVID-19 e complicações cardiovasculares do DM. METODOLOGIA: Foi realizada revisão sistemática compreendendo publicações a partir da identificação do Sars-Cov-2 até junho de 2021 nas bases de dados MEDLINE/VIA PUBMED, SCOPUS e Web of Science, utilizando-se rigor PRISMA. RESULTADOS: As buscas resultaram na inclusão de 13 artigos elegíveis. Foi possível determinar a incidência de complicações cardiovasculares em diabéticos com COVID-19, além de verificar novos casos de DM pós-infecção e observar maior mortalidade em portadores de DM. DISCUSSÃO: Ainda são escassos os estudos que apontam a relação da COVID-19 e o desenvolvimento ou exacerbação de complicações cardiovasculares em portadores de DM. Uma das complicações mais presentes foi a lesão cardíaca aguda, enquanto as comorbidades mais encontradas foram hipertensão, DCV e doença renal crônica. CONCLUSÃO: Há relação entre COVID-19, DCV e DM, sendo a combinação dos três maior fator de letalidade. São necessários mais estudos que investiguem os desfechos a médio e longo prazo do dano endotelial e do ambiente inflamatório presentes nos pacientes diabéticos.
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